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Mixing Covid-19 vaccines tied to more side effects, early UK data suggests Researchers in the United Kingdom reported last week that people who got mixed doses of coronavirus vaccines -- receiving a different vaccine type as a second dose than the first does -- appear to be more likely to experience mild side effects such as fever, chills, fatigue or headache. "We are right now in the middle of these trials and the data are coming as we speak," Pfizer CEO Albert Bourla told Axios during a virtual event on Wednesday. "The data that I see coming, they are supporting the notion that likely there will be a need for a booster somewhere between. So, if it's the same vaccine, my understanding is that what would have to happen the CDC would have to recommend an additional dose with details around when that should occur," Moss said. If it's a modified vaccine, "this is where things get interesting and I don't think we quite know," he said but added that the regulatory process could be similar to what happens with flu vaccines each year in February, noting that manufacturers should "generate the data to support authorization" of a modified vaccine. "Further discussions will be necessary to decide whether, in the future, modified COVID-19 vaccines may be authorized without the need for clinical studies," according to the guidance. But overall, vaccine developers are "encouraged" to perform exploratory studies on modified vaccines to boost immune responses many of them saying that their personal liberties had been infringed upon. "You are trampling on the Constitution by agreeing to extend Dr. Kaiser's recommendations," declared one resident. Another said: "When we are inside, locked up because of health orders by Dr. Kaiser, we are weak. The American people are a free people." asked the Riverside County Board of Supervisors about Kaiser's position and they replied by thanking Kaiser for his service and noting.

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